The aim of this study is to evaluate the adhesion ability of okra gum, which is gaining\npopularity as a tablet binder. For this purpose, gum was extracted from okra pods, and the binding\nstrength of different concentrations (1%, 3%, and 5%) was determined quantitatively. Additionally,\nnaproxen sodium tablets were prepared by using okra gum as a binder and were evaluated for\ntheir properties including hardness, friability, disintegration time, and dissolution rate. The binding\nstrength values were compared with that of pre-gelatinized starch, a commonly used tablet binder.\nThe results from universal testing machine indicate that the binding strengths of all dispersions of okra\nincrease as the concentration increases from 1% to 5% and ranges from 2.5 to 4.5 N, which are almost\ntwice a high as those of pre-gelatinized starch. The tablets prepared with okra gum have shown good\nmechanical strength with hardness values of 7ââ?¬â??8.5 kg/cm2 and a friability <1%, comparable to tablets\nprepared with starch. The disintegration time was longer (7.50 min with okra gum and 5.05 min with\nstarch paste), and the drug release from these tablets was slower than the formulations with starch.\nThe higher binding ability of okra gum probably linked with its chemical composition as it mainly\ncontains galactose, rhamnose, and galacturonic acid. This study concludes that okra gum is a better\nbinder than pre-gelatinized starch, it might be explored in future for introduction as a cost-effective\nbinder in the pharmaceutical industry.
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